The dawn of post antibiotic era: Are we prepared?

Resistance to antibiotics: are we in the post-antibiotic era?

Serious infections caused by bacteria that have become resistant to commonly used antibiotics have become a major global healthcare problem in the 21st century. They not only are more severe and require longer and more complex treatments, but they are also significantly more expensive to diagnose and to treat. Antibiotic resistance, initially a problem of the hospital setting associated with an...

Keynote I: The era of heterogeneity: Are we prepared?

Usage models and applications are rapidly changing as a new class of devices (smart phones, smart TVs, etc) and rich cloud computing services (on datacenter servers) enter the marketplace. In this talk, I will start by describing some key examples of these radical changes in usage models, applications and devices. I will then highlight why the next decade of computing (clients and servers) will...

Benefits and Challenges of Antivirulence Antimicrobials at the Dawn of the Post-Antibiotic Era

DOI: 10.2174/22103031066661605061200 57 Abstract: In April 2014, the World Health Organization announced the beginning of a post-antibiotic era and declared antimicrobial resistance (AMR) a public health priority demanding global action. If no action is taken, by 2050 AMR will kill more people each year than cancer, with 10 million estimated annual deaths at a cost of $100 trillion to the globa...

Novel antibiotics: Are we still in the pre–post-antibiotic era?

PURPOSE Therapeutic efficacy and safety in infections due to multidrug-resistant bacteria can be improved by the clinical development of new compounds and devising new derivatives of already useful antibiotics. Due to a striking global increase in multidrug-resistant Gram-positive but even more Gram-negative organisms, new antibiotics are urgently needed. METHODS This paper provides a review ...

disaster: are we prepared?